Gen-Plus skin permeation center

Our skin permeation competence center offers several methods for in vitro permeation studies (using human skin, porcine skin, porcine buccal mucosa etc.) as well as the investigation of penetration into the skin (using tape stripping and cryomicrotomization of skin samples).

For example- by using the P.L.E.A.S.E.® - Laser technology the permeation rate even of small peptides with1.000 Da could be increased by factor 300!

Gen-Plus drug delivery technologies

Gen-Plus offers a wide range of formulation technologies suited for improving  biopharmaceutical properties, stability and taste masking incl. proprietary rights options for:

  • Transdermal drug delivery systems
  • Oral thin films
  • Cyclodextrin-inclusion-concepts
  • API-modification with aid of mesoporous carriers e.g. silica particles, aluminium-magnesium silicates
  • Production of solid solutions or solid dispersions
  • Amorphisation of APIs
  • Hot-melt-extrusion
  • Spray drying
  • Lyophilisation
  • Micro-/nanoemulsions, e.g. SNEDDS

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